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Updated: Feb 9, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

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Biatrial versus Isolated Left Atrial Ablation in Atrial Fibrillation: A Systematic Review and Meta-Analysis

Hongmu Li1, Xifeng Lin2, Xun Ma3

  • 1Department of Cardiovascular Surgery, Quanzhou First Hospital of Fujian Medical University, Quanzhou 362000, China.

Biomed Research International
|June 2, 2018
PubMed

Insights

Biatrial ablation (BA) and left atrial ablation (LA) for atrial fibrillation show similar sinus rhythm restoration and event rates. However, biatrial ablation leads to a higher need for permanent pacemaker implantation.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Interventions

Background:

  • Atrial fibrillation (AF) management often involves catheter ablation.
  • The comparative effectiveness of biatrial ablation (BA) versus isolated left atrial ablation (LA) for AF requires further investigation.

Purpose of the Study:

  • To compare the clinical outcomes of biatrial ablation (BA) and isolated left atrial ablation (LA) in patients with atrial fibrillation through a meta-analysis.

Main Methods:

  • A comprehensive electronic literature search was conducted up to December 2016.
  • Twenty-one studies involving 3609 patients were included in this meta-analysis.
  • Outcomes were analyzed using odds ratios and weighted mean differences with 95% confidence intervals.

Main Results:

  • Both BA and LA demonstrated similar sinus rhythm prevalence at discharge, 12 months, and beyond.
  • A higher sinus rhythm prevalence was observed in the BA group at 6 months post-procedure.
  • The rate of permanent pacemaker implantation was significantly higher in the BA group compared to the LA group.
  • No significant differences were found in 30-day and late mortality or neurological events between the two groups.

Conclusions:

  • Biatrial ablation and left atrial ablation yield comparable rates of restored sinus rhythm and similar risks of mortality and cerebrovascular events.
  • Biatrial ablation is associated with an increased rate of permanent pacemaker implantation compared to left atrial ablation.
Abstract

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