Risk factors for positioning-related somatosensory evoked potential changes in 3946 spinal surgeries

The goal of this study was to evaluate the risk factors associated with positioning-related SSEP changes (PRSC). The study investigated the association between 18 plausible risk factors and the occurrence of intraoperative PRSC. Risk factors investigated included demographic variables, comorbidities, and procedure related variables. All patients were treated by the University of Pittsburgh Medical Center from 2010 to 2012. We used univariate and multivariate statistical methods. 69 out of the 3946 (1.75%) spinal surgeries resulted in PRSC changes. The risk of PRSC was increased for women (p < 0.001), patients older than 65 years of age (p = 0.01), higher BMI (p < 0.001) patients, smokers (p < 0.001), and patients with hypertension (p < 0.001). No associations were found between PRSC and age greater than 80 years, diabetes mellitus, cardiovascular disease, and peripheral vascular disease. Three surgical situations were associated with PRSC including abnormal baselines (p < 0.001), patients in the "superman" position (p < 0.001), and patients in surgical procedures that extended over 200 min (p = 0.03). Patients with higher BMIs and who are undergoing spinal surgery longer than 200 min, with abnormal baselines, must be positioned with meticulous attention. Gender, hypertension, and smoking were also found to be risk factors from their odds ratios.