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[Brachytherapy for head and neck cancers].

D Peiffert1, B Coche-Dequéant2, M Lapeyre3

  • 1Département de radiothérapie, institut de cancérologie de Lorraine Alexis-Vautrin, avenue de Bourgogne, 54511, Vandœuvre-lès-Nancy, France.

Cancer Radiotherapie : Journal De La Societe Francaise De Radiotherapie Oncologique
|June 3, 2018
PubMed
Summary

Brachytherapy is effective for limited head and neck cancers like lip and oral tumors. Modern techniques, including pulsed and high dose rate brachytherapy, offer optimized treatment and improved outcomes.

Keywords:
BrachytherapyCancerCancersCuriethérapieDébit pulséHDDHaut débitHead and neckHigh dose rateLow dose ratePDRPulse dose rateRadiotherapyRadiothérapieTête et cou

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Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Physics

Background:

  • Brachytherapy is a key treatment for specific head and neck cancers.
  • Nasopharyngeal tumors are now managed with intensity-modulated radiotherapy.
  • Brachytherapy techniques have evolved from low dose rate (LDR) to pulsed dose rate (PDR) and high dose rate (HDR).

Purpose of the Study:

  • To report the GEC-ESTRO 2017 recommendations for brachytherapy in head and neck cancers.
  • To integrate historical LDR data with current PDR and HDR brachytherapy findings.
  • To provide an updated overview of brachytherapy techniques and outcomes.

Main Methods:

  • Review of historical low dose rate brachytherapy data.
  • Inclusion of data from pulsed dose rate and high dose rate brachytherapy series.
  • Consideration of intensity-modulated radiotherapy for nasopharyngeal tumors.

Main Results:

  • Limited tumors of the lip, nose, oral cavity, and oropharynx are primary indications for brachytherapy.
  • Intensity-modulated radiotherapy is standard for nasopharyngeal tumors, used exclusively, adjunctively, or postoperatively.
  • Pulsed dose rate brachytherapy allows dose rate prescription and optimized dose distribution, with HDR results now published.

Conclusions:

  • Brachytherapy remains crucial for specific head and neck malignancies.
  • Advancements in PDR and HDR brachytherapy offer improved treatment optimization.
  • The GEC-ESTRO recommendations synthesize historical and modern brachytherapy data for clinical guidance.