Related Experiment Video
Updated: Feb 9, 2026

Author Spotlight: Advancing Pathogen Detection and Disease Assessment in Real-Time Using M-ROSE
Published on: March 1, 2024
[Hormesis of drugs for infectious diseases]
Abstract:
Hormesis, a biphasic dose-response phenomenon characterized by low-dose stimulation and high-dose inhibition, is a common feature of medicines but neglected sometime. Understanding of hormesis is essential for drug discovery and clinical application. Assessing hormetic range needs a proper experiment design including the number of doses and dose spacing, especially in the low dose zone. This article provides the shapes of hormetic dose-response curves, underlying mechanisms and the significance of hormesis for drugs of infectious diseases to facilitate drugs development and clinical applications.
Related Concept Videos
Effect of Hepatic Disease on Pharmacokinetics: Active Drug, Metabolite and Fraction of Metabolized Drug
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Factors Influencing Drug Absorption: Disease States and Pharmacology
Substances such as alcohol and specific drugs, including antineoplastics, can also negatively impact drug absorption. For instance,...
Acid Suppressive Drugs for Peptic Ulcer Disease: Antacids
However, this neutralization reaction between...
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant

