Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Merkel-cell tumor].

S Bassas, J Ferrando, J A Bombi

    Medicina Cutanea Ibero-Latino-Americana
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    This case study describes a Merkel cell tumor in a 77-year-old woman. Surgical treatment led to a positive outcome with the patient remaining asymptomatic two years post-operation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Observation of the γγ→ττ Process in Pb+Pb Collisions and Constraints on the τ-Lepton Anomalous Magnetic Moment with the ATLAS Detector.

    Physical review letters·2023
    Same author

    Observation of an Excess of Dicharmonium Events in the Four-Muon Final State with the ATLAS Detector.

    Physical review letters·2023
    Same author

    Strong Constraints on Jet Quenching in Centrality-Dependent p+Pb Collisions at 5.02 TeV from ATLAS.

    Physical review letters·2023
    Same author

    Search for Heavy Neutral Leptons in Decays of W Bosons Using a Dilepton Displaced Vertex in sqrt[s]=13  TeV pp Collisions with the ATLAS Detector.

    Physical review letters·2023
    Same author

    Test of CP Invariance in Higgs Boson Vector-Boson-Fusion Production Using the H→γγ Channel with the ATLAS Detector.

    Physical review letters·2023
    Same author

    Observation of WWW Production in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

    Physical review letters·2022
    Same journal

    [Acquired bullous epidermolysis and multiple myeloma].

    Medicina cutanea ibero-latino-americana·1990
    Same journal

    [Eosinophilic ulcer of the tongue. Pathogenic role of eosinophils].

    Medicina cutanea ibero-latino-americana·1990
    Same journal

    [Facial granuloma caused by cactus bristles].

    Medicina cutanea ibero-latino-americana·1990
    Same journal

    [Epithelioid sarcoma. Immunohistochemical study. Therapy with recombinant alfa interferon].

    Medicina cutanea ibero-latino-americana·1990
    Same journal

    [Dyshidrosiform pemphigoid].

    Medicina cutanea ibero-latino-americana·1990
    Same journal

    [Metastatic alopecia].

    Medicina cutanea ibero-latino-americana·1990
    See all related articles

    Area of Science:

    • Oncology
    • Dermatopathology
    • Surgical Pathology

    Background:

    • Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer.
    • The preauricular region is an uncommon site for Merkel cell tumor presentation.
    • Early diagnosis and prompt surgical intervention are crucial for favorable outcomes in MCC.

    Observation:

    • A Merkel cell tumor was identified in the preauricular region of a 77-year-old female patient.
    • Histopathological examination revealed a characteristic nodular and trabecular pattern with specific cellular morphology.
    • Electron microscopy identified key ultrastructural features, including microfilaments and dense core granules.

    Findings:

    • The Merkel cell tumor exhibited characteristic histological features: oval/elongated cells, poor basophilic cytoplasm, and large nuclei with prominent nucleoli.

    Related Experiment Videos

  • Ultrastructural analysis via electron microscopy confirmed polygonal cells with irregular nuclei and dense core granules with clear halos.
  • Tissular hormonal determinations were within normal limits, suggesting no significant endocrine dysfunction associated with the tumor.

    • Implications:

    • This case highlights the importance of considering Merkel cell tumors in the differential diagnosis of preauricular masses.
    • The findings underscore the utility of integrating histological, electron microscopic, and hormonal studies for comprehensive Merkel cell tumor characterization.
    • The patient's asymptomatic status two years post-surgery suggests that radical surgical excision can be an effective treatment for localized Merkel cell carcinoma.