The unfaithful neuritis
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Updated: Oct 2, 2026

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
Published on: April 14, 2014
Luca De Simone1, Francesco Pellegrini2, Daniele Cirone3
1Department of Ophthalmology, University Campus Bio-Medico of Rome, Rome, Rome, Italy; Immunology Eye Unit, Azienda USL IRCCS, Reggio Emilia, Reggio Emilia, Italy.
Abstract:
A 55-year-old man with a history of mantle cell lymphoma reported acute blurred vision in the right eye. Although initially diagnosed with acute retrobulbar optic neuritis, 3 weeks later retinal infiltrates and vitritis developed, but vitrectomy resulted negative for vitreoretinal lymphoma. Further investigation revealed a serology positive for syphilis. This case highlights the role of the ophthalmologist in the diagnosis of syphilis, which is able to mimick multiple eye disorders, optic neuritis, and vitreoretinal lymphoma among others.
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