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![Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F62460.jpg&w=3840&q=50)
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Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
Published on: July 1, 2021
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Brown and beige fat: From molecules to physiology
Maria Chondronikola1, Labros S Sidossis2
1Center for Human Nutrition, Washington University School of Medicine, St. Louis, United States; Harokopio University of Athens, Greece.
Summary
Brown adipose tissue (BAT) and the browning of white adipose tissue (WAT) show promise for combating obesity. Further research is needed to fully understand their role in human metabolism and disease.
Area of Science:
- Metabolic Physiology
- Adipose Tissue Biology
- Obesity Research
Background:
- Recent discoveries highlight brown adipose tissue (BAT) and white adipose tissue (WAT) browning in humans.
- Adipose tissue is increasingly recognized as a therapeutic target for obesity and metabolic disorders.
Purpose of the Study:
- To critically evaluate the physiological significance of BAT and WAT browning in human metabolic function.
- To discuss factors influencing BAT and WAT browning regulation in humans.
Main Methods:
- Literature review of current scientific evidence.
- Analysis of studies on adipose tissue physiology and regulation.
Main Results:
- Current literature supports BAT and WAT browning as promising targets for obesity interventions.
- Evidence suggests a significant role in human metabolic health and disease.
Conclusions:
- BAT and WAT browning represent emerging therapeutic targets for obesity and related metabolic complications.
- Further investigation is crucial to elucidate their precise physiological roles and regulatory mechanisms in humans.
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