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Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad

E S Buys1, D P Zimmer1, J Chickering1

  • 1Ironwood Pharmaceuticals Inc., 301 Binney St, Cambridge, MA, USA.

Nitric Oxide : Biology and Chemistry
|June 4, 2018
PubMed

Keywords:
Drug developmentFibrosisGuanylyl cyclaseIWP-051InflammationMetabolismMultidimensional pharmacologyNeuronal functionNitric oxideOlinciguatPraliciguatSmooth muscle functionStimulatorVascular function

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