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Purposeless Groaning in Parkinson's Disease
Shen-Yang Lim1,2, Ai Huey Tan1,2, Jia Lun Lim2,3
1Division of Neurology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Journal of Movement Disorders
|June 5, 2018
Summary
Purposeless groaning, a symptom seen in progressive supranuclear palsy, can also occur in advanced Parkinson's disease. Recognizing this vocalization aids clinicians in avoiding unnecessary treatments and investigations.
Area of Science:
- Neurology
- Movement Disorders
- Clinical Case Reports
Background:
- Purposeless groaning is a rare vocalization reported in advanced neurological conditions.
- It has been primarily associated with progressive supranuclear palsy.
- The underlying pathophysiology is thought to involve frontal-subcortical dysfunction.
Purpose of the Study:
- To report a case of purposeless groaning as a primary complaint in advanced Parkinson's disease.
- To highlight the clinical significance of recognizing this symptom in Parkinson's disease.
Main Methods:
- Case presentation of a patient with advanced Parkinson's disease experiencing purposeless groaning.
- Review of existing literature on purposeless groaning in neurodegenerative diseases.
Main Results:
- The patient presented with purposeless groaning as a chief complaint, distinct from typical Parkinson's symptoms.
- The symptom is hypothesized to stem from disinhibition and perseveration linked to frontal-subcortical circuits.
Conclusions:
- Purposeless groaning can manifest in advanced Parkinson's disease, not exclusively in progressive supranuclear palsy.
- Clinical awareness is crucial to prevent misdiagnosis and unnecessary interventions, such as opioid prescriptions.