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Updated: Feb 9, 2026

Derivation and Differentiation of Canine Ovarian Mesenchymal Stem Cells
Published on: December 16, 2018
Sebaceous cell differentiation in a canine oral papilloma
Du-Gyeong Gang1,2, Cheul-Hyeon Sim1,2, Tae-Je Lee1,2
1Institute of Animal Medicine, Gyeongsang National University, Jinju, Republic of Korea (Gang, Kong, Hong).
Abstract:
Papillomas caused by viral infection are well-known tumors in animals. Microscopic features typically include neoplastic epithelium with hyperkeratosis and koilocytes. An 8-y-old castrated male Shih Tzu dog was presented with a small exophytic mass on the external upper lip. The mass was diagnosed as a viral papilloma based on microscopic and immunohistochemical examination. Sebaceous cell differentiation was found in the neoplastic epithelium of the tumor, which is a rare finding in humans or animals.
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