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Related Concept Videos

Mesh Analysis01:20

Mesh Analysis

1.5K
Mesh analysis is a valuable method for simplifying circuit analysis using mesh currents as key circuit variables. Unlike nodal analysis, which focuses on determining unknown voltages, mesh analysis applies Kirchhoff's voltage law (KVL) to find unknown currents within a circuit. This method is particularly convenient in reducing the number of simultaneous equations that need to be solved.
A fundamental concept in mesh analysis is the definition of meshes and mesh currents. A mesh is a closed...
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Location and Orientation of the Heart01:13

Location and Orientation of the Heart

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The human heart, despite its modest size and weight, is an organ of remarkable strength and endurance. Roughly the size of a fist, the heart weighs between 250 and 350 grams and is nestled within the mediastinum, the medial cavity of the thorax. It extends obliquely for about 12 to 14 cm, resting on the superior surface of the diaphragm. The heart is positioned anterior to the vertebral column and posterior to the sternum, with two-thirds of its mass lying to the left of the midsternal line.
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Mesh Analysis with Current Sources01:10

Mesh Analysis with Current Sources

2.0K
Mesh analysis becomes simpler when analyzing circuits with current sources, whether independent or dependent. The presence of current sources reduces the number of equations required for analysis. Two cases illustrate this:
Current Source in One Mesh: The analysis process is straightforward when a current source is found in only one mesh within the circuit. Mesh currents are assigned as usual, with the mesh containing the current source excluded from the analysis. Kirchhoff's voltage law...
2.0K
Poisson's Ratio01:23

Poisson's Ratio

1.2K
Poisson's ratio is a material property that indicates their stress response. It explains the connection between the elongation or compression a material undergoes in the direction of an applied force and the contraction or expansion it experiences perpendicular to that force. When a slender bar is loaded axially, it stretches in the direction of the force and contracts laterally. Poisson's ratio is the negative ratio of this lateral contraction to the axial elongation. The negative sign...
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Odds Ratio01:09

Odds Ratio

1.9K
The odds ratio (OR) is a statistical measure used extensively in epidemiology and research to quantify the strength of association between exposure and outcome across different groups. Unlike relative risk, which compares the probabilities of an event occurring, the odds ratio compares the odds of an event occurring in the exposed group to the odds of it occurring in the unexposed group. The odds, in this context, are calculated as the probability of the event happening divided by the...
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Hazard Ratio01:12

Hazard Ratio

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The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
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Related Experiment Video

Updated: Feb 9, 2026

Transvaginal Mesh Insertion in the Ovine Model
10:32

Transvaginal Mesh Insertion in the Ovine Model

Published on: July 27, 2017

17.0K

Graft orientation influences meshing ratio.

Lukas Capek1, Cormac Flynn2, Martin Molitor3

  • 1Technical University of Liberec, Department of Structure and Technologies, Studentska 2, 46117 Liberec 1, Czech Republic.

Burns : Journal of the International Society for Burn Injuries
|June 5, 2018
PubMed
Summary
This summary is machine-generated.

The orientation of Langer's lines significantly impacts meshed skin graft expansion. Aligning mesh incisions with Langer's lines optimizes graft expansion, reducing discrepancies between intended and actual graft size.

Keywords:
BiomechanicsBurnFinite element methodLanger line

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Area of Science:

  • Biomedical Engineering
  • Dermatology
  • Materials Science

Background:

  • Meshed skin grafting, a technique since the 1960s, aims to expand skin grafts for wound coverage.
  • A known issue is the discrepancy between the intended and actual expansion ratio of meshed skin grafts.
  • The factors influencing this expansion variability require further investigation.

Purpose of the Study:

  • To investigate the hypothesis that Langer's lines orientation is critical for the expansion ratio of meshed skin grafts.
  • To analyze the relationship between Langer's lines and the mechanical behavior of meshed skin grafts.

Main Methods:

  • Ex vivo uniaxial tests of human skin were conducted to gather data for a constitutive model.
  • Finite element analyses were performed to simulate the skin graft meshing process.
  • Stress distributions and expansion ratios were determined under various conditions.

Main Results:

  • True stress peaks were consistently observed around the mesh pattern vertices.
  • Achieving the declared expansion ratio was impossible when meshing incisions were perpendicular to Langer's lines.
  • The maximum difference between declared and real expansion ratio reached 37%.

Conclusions:

  • The orientation of Langer's lines relative to the meshing direction is a significant factor in skin graft expansion.
  • This finding helps explain the observed scatter in data regarding meshed skin graft expansion ratios.
  • Optimizing graft meshing based on Langer's lines can improve clinical outcomes.