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Updated: Feb 9, 2026
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Application of a New Mesh Fixation Method in Laparoscopic Incisional Hernia Repair
Published on: December 23, 2022
7.5K
Urinary Bladder Matrix Reinforcement for Laparoscopic Hiatal Hernia Repair
John Zografakis1, Gregory Johnston2, Jennifer Haas1
1Department of Surgery.
Summary
Porcine urinary bladder matrix (UBM) mesh is a safe and effective reinforcement for laparoscopic hiatal hernia repair (LHHR). This biological mesh reduced recurrence rates and improved patient symptoms, offering benefits over other biomaterials.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Biomaterials Science
Background:
- Laparoscopic hiatal hernia repair (LHHR) recurrence rates can be reduced with synthetic or biologic mesh reinforcement.
- Urinary bladder matrix (UBM) is a biologically derived extracellular matrix with demonstrated clinical success.
Purpose of the Study:
- To evaluate the safety and efficacy of using porcine UBM mesh for reinforcement during LHHR.
Main Methods:
- Retrospective review of 62 patients undergoing LHHR with porcine UBM mesh reinforcement (August 2009 - May 2014).
- Primary outcomes included recurrence (>2-cm defect at 3 months), complications, pre/postoperative GERD or dysphagia, and PPI cessation.
Main Results:
- 19% recurrence rate at 3 months post-surgery.
- 75% improvement in dysphagia (P = .05), with 16% remaining symptomatic.
- No intraoperative complications; one unrelated postoperative mortality.
Conclusions:
- Porcine UBM mesh is a safe and effective reinforcement for LHHR.
- UBM mesh demonstrated reduced recurrence rates compared to unreinforced repairs.
- UBM's tissue remodeling properties may offer advantages over other biologic meshes.
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