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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
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Tuberculosis in the Circumpolar Region, 2006-2012.

A-C Bourgeois1, T Zulz2, M G Bruce2

  • 1Centre for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, Ontario, Canada.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease
|June 5, 2018
PubMed
Summary
This summary is machine-generated.

Tuberculosis (TB) remains a significant public health concern in northern circumpolar regions. Surveillance data reveal varying incidence rates and drug resistance patterns, highlighting the need for improved TB control strategies.

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Area of Science:

  • Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • Tuberculosis (TB) poses a substantial public health challenge in the northern circumpolar regions.
  • Understanding the epidemiology of TB in these diverse populations is crucial for effective control.
  • Previous data on TB characteristics in the Arctic and sub-Arctic are limited.

Purpose of the Study:

  • To describe and compare demographic, clinical, and laboratory features of tuberculosis cases.
  • To analyze drug resistance and treatment completion rates among northern circumpolar populations.
  • To inform public health strategies for TB control in the Arctic and sub-Arctic.

Main Methods:

  • A descriptive analysis of active tuberculosis cases reported between 2006 and 2012.
  • Evaluation of incidence rates (IR), age and sex distribution, and diagnostic characteristics.
  • Assessment of drug resistance patterns and treatment completion rates across jurisdictions.

Main Results:

  • TB incidence rates varied significantly, from 4.3/100,000 in Northern Sweden to 199.5/100,000 in Nunavik, Canada.
  • Higher incidence rates were observed in males across all regions; Yukon reported the highest proportion of new cases.
  • Multidrug-resistant tuberculosis ranged from 0% to 46.3%, with varied treatment completion rates.

Conclusions:

  • Tuberculosis remains a serious public health issue in circumpolar regions, necessitating ongoing surveillance.
  • Surveillance data are vital for enhancing the understanding and control of TB in the north.
  • Targeted interventions may be required based on regional variations in TB epidemiology and resistance.