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Updated: Feb 9, 2026

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Preoperative intraaortic balloon pump before urgent coronary bypass grafting
Ingo Slottosch1, Oliver Liakopoulos2, Maximilian Scherner1
11 Department of Cardiothoracic Surgery, University Hospital Magdeburg, Magdeburg, Germany.
Insights
Preoperative intraaortic balloon pump support in urgent coronary artery bypass grafting for acute coronary syndrome did not improve outcomes. This high-risk intervention showed no significant reduction in mortality or major adverse events after propensity-score matching.
Area of Science:
- Cardiology
- Cardiac Surgery
- Vascular Interventions
Background:
- Urgent or emergency coronary artery bypass grafting (CABG) for acute coronary syndrome (ACS) carries significant risks.
- Intraaortic balloon pump (IABP) support is a potential intervention for high-risk cardiac surgery patients.
Purpose of the Study:
- To evaluate the clinical impact of preoperative intraaortic balloon pump (IABP) support in patients undergoing urgent or emergency CABG for ACS.
- To assess the effect of IABP on postoperative mortality and major adverse cardiovascular and cerebrovascular events (MACCE).
Main Methods:
- Retrospective review of a single institutional database (April 2010 - December 2016).
- Analysis of 1066 patients with ACS requiring urgent/emergency CABG.
- Propensity-score matching was employed to compare outcomes between IABP and control groups.
Main Results:
- Preoperative IABP use was associated with higher unadjusted mortality (20% vs. control).
- After propensity-score matching, no significant differences were observed in all-cause mortality (20.0% vs. 18.2%), cardiac mortality (18.2% vs. 14.5%), or MACCE (29.1% vs. 27.3%).
- Overall hospital mortality was 8.8% in the study cohort.
Conclusions:
- Preoperative intraaortic balloon pump support does not provide additional clinical benefit for patients undergoing urgent or emergency CABG for acute coronary syndrome.
- The findings suggest that preoperative IABP is not associated with improved outcomes in this specific high-risk patient population.
Abstract:
Background Urgent or emergency coronary artery bypass grafting in patients with acute coronary syndrome is associated with increased morbidity and mortality. We investigated the effects of preoperative intraaortic balloon pump support in this high-risk patient cohort. Methods Our institutional database was retrospectively reviewed for patients with acute coronary syndrome and an urgent or emergency indication for coronary artery bypass from April 2010 to December 2016. Data of 1066 patients were analyzed. We assessed the impact of preoperative intraaortic balloon pump therapy on postoperative mortality and major adverse cardiovascular and cerebrovascular events, and performed propensity-score matching. Results Intraaortic balloon pump support was implemented in 223 (20.9%) patients: 55 (5.2%) preoperatively and 168 (15.8%) intra- or postoperatively. Overall hospital mortality was 8.8%. Patients with a preoperative intraaortic balloon pump had increased mortality (11/55, 20%) compared to controls ( p = 0.006). After propensity-score matching, all-cause mortality (20.0% vs. 18.2%, p = 0.834), cardiac mortality (18.2% vs. 14.5%, p = 0.651), and major adverse cardiovascular and cerebrovascular events (29.1% vs. 27.3%, p = 0.855) were comparable between groups. Conclusions Preoperative intraaortic balloon pump support does not confer any additional clinical benefit on patients undergoing coronary artery bypass grafting for acute coronary syndrome.
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