Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Depressive Disorders: Etiology

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...

Depressive Disorders: MDD and Dysthymia

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...

Freezing Point Depression and Boiling Point Elevation

Freezing Point Depression and Boiling Point Elevation

Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...

Depressants

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Nonsuicidal self-injury in eating disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2022

Same author

[Catecholamine excretion in patients with eating disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2015

Same author

[In depth study of troubles in sexual development and behavior associated with anorexia nervosa].

Revue medicale suisse·2011

Same author

[Borderline mental disorders in patients with prostate cancer].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2003

Same author

[Modeling and experimental therapy of myocardial infarct in dogs].

Fiziolohichnyi zhurnal·1978

Same author

[Pathomorphologic basis for the method of preparing the bronchial stump in experimental lung resection].

Klinicheskaia khirurgiia·1971

Same journal

[The role of the cerebellum in the coordination of brain activity and the development of autism spectrum disorders].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same journal

[A clinical case of anxiety-hypochondriacal depression with extensive somatized symptoms in the elderly].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same journal

[De novo variant in the ATP2B2 gene as a cause of neuropsychiatric developmental disorder].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same journal

[Electroencephalographic predictors of olfactory stimulus discrimination in COVID-19 survivors].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same journal

[Effect of long-term carbamazepine therapy on bone metabolism in women with epilepsy].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

Same journal

[Glial-derived neurotrophic factor and neuropsychological status in COVID-19 survivors].

Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 9, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

[Cerebral cryptococcosys with depressive disorder].

M S Artemieva¹, I I Yurovskaya¹, A N Gavrik¹

¹Peoples' Friendship University of Russia, Moscow, Russia.

Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova

|June 5, 2018

Summary

This summary is machine-generated.

Cerebral cryptococcosis, a serious CNS infection caused by Cryptococcus neoformans, can present with subtle neurological and behavioral changes. This case highlights the importance of considering fungal meningitis in patients with atypical psychiatric and neurological symptoms.

Keywords:

anxiety cerebral cryptococcosis depressive episode fungal infection

More Related Videos

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Published on: July 7, 2023

Related Experiment Videos

Last Updated: Feb 9, 2026

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Published on: July 7, 2023

Area of Science:

Infectious Diseases
Neurology
Mycology

Background:

Cryptococcus neoformans is a significant human pathogen, frequently impacting the lungs and Central Nervous System (CNS).
CNS involvement commonly manifests as cryptococcal meningitis, a serious infection.
Early diagnosis and treatment are crucial for managing cryptococcal infections.

Observation:

A case of cerebral cryptococcosis is presented.
The patient initially exhibited non-specific anxiety-depressive symptoms.
Neurological deficits and behavioral changes subsequently developed.

Findings:

The case illustrates a less typical presentation of cerebral cryptococcosis.
The study emphasizes the diverse clinical manifestations of CNS fungal infections.
Diagnostic challenges associated with atypical presentations are highlighted.

Implications:

This case underscores the need for a broad differential diagnosis in patients with unexplained neurological and psychiatric symptoms.
Recognizing subtle signs of cerebral cryptococcosis can lead to earlier intervention.
Further research into the varied presentations of fungal CNS infections is warranted.