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Related Experiment Video

Updated: Feb 9, 2026

A Cryoinjury Model to Study Myocardial Infarction in the Mouse

A Cryoinjury Model to Study Myocardial Infarction in the Mouse

Published on: September 19, 2019

Myocardial infarction and alcohol consumption: A case-control study.

Milena Ilic¹, Sandra Grujicic Sipetic², Branko Ristic³

¹Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia.

|June 5, 2018

Summary

Binge drinking significantly increases myocardial infarction risk, especially in older males and rural residents. This public health issue warrants attention in populations with high alcohol consumption.

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Area of Science:

Cardiology
Epidemiology
Public Health

Background:

While moderate alcohol intake may benefit heart health, the effects of heavy drinking episodes remain unclear.
Epidemiological studies show a strong link between low alcohol consumption and reduced myocardial infarction risk.
The impact of heavy alcohol consumption, particularly binge drinking, on acute myocardial infarction risk requires further investigation.

Purpose of the Study:

To investigate the association between alcohol consumption patterns and the risk of acute myocardial infarction.
To determine if binge drinking is a significant risk factor for myocardial infarction.

Main Methods:

A hospital-based case-control study was conducted in Serbia with 374 participants (187 myocardial infarction patients and 187 controls).
Participants were matched by gender, age, and place of residence.
Logistic regression analysis was used to calculate odds ratios (OR) and 95% confidence intervals (95% CI).

Main Results:

Binge drinking in the past 12 months was significantly more prevalent in myocardial infarction cases (25.1%) than in controls (12.8%).
Binge drinking was associated with an adjusted odds ratio of 2.2 for myocardial infarction.
Increased risk was particularly noted in older individuals (OR=5.1), males (OR=2.3), and those residing in rural areas (OR=4.8).

Conclusions:

Binge drinking is associated with a doubled risk of myocardial infarction.
The findings highlight binge drinking as a significant public health concern, especially in populations with high alcohol consumption like Serbia.
Public health strategies should consider the impact of binge drinking on myocardial infarction incidence.