Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Fischer Projections

Fischer Projections

Learning to draw Fischer projections of molecules and understanding their relevance plays a crucial role in the visual depiction of organic molecules. A Fischer projection is a two-dimensional projection on a planar surface to simplify the three-dimensional wedge–dash representation of molecules. This is especially helpful in the case of molecules with multiple chiral centers that can be difficult to draw. Here, all the bonds of interest are represented as horizontal or vertical lines. While...

Newman Projections

Newman Projections

Different notations are used to represent the three-dimensional structure of molecules on two-dimensional surfaces. One of the most commonly used representations is the dash-wedge formula. The dashed wedges, solid wedges, and the plane lines indicate the groups situated behind the plane, coming out of the plane, and in the plane, respectively.
The organic molecules rotate across the single bonds leading to numerous temporary three-dimensional structures of varying energy known as...

Aging

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...

System of Memory

System of Memory

Memory is categorized into three major systems: sensory memory, short-term memory (STM), and long-term memory (LTM). These systems differ in their capacity and the duration for which they can hold information. Sensory memory captures raw sensory input from the environment, holding it for just a few seconds or less. For example, on hearing a brief, loud sound, like a car horn honking, the sound seems to linger in the mind for a moment even after it stops. This is an instance of sensory memory...

Working Memory

Working Memory

Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...

Coordinates and Map Projections

Coordinates and Map Projections

Coordinates and map projections are essential tools in accurately representing the Earth's surface for various applications, ranging from navigation to spatial analysis. The latitude and longitude coordinate system is a universally recognized framework for defining locations. Latitude specifies the distance of a point north or south of the equator, measured in degrees from 0° at the equator to 90° at the poles. Longitude indicates a location's position east or west of the prime meridian,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Integrating dorsolateral prefrontal cortex multi-omics and GWAS summary data reveals genetic etiology of Parkinson's disease.

medRxiv : the preprint server for health sciences·2026

Same author

Integrating dorsolateral prefrontal cortex multi-omics and GWAS summary data reveals genetic etiology of Parkinson's disease.

Research square·2026

Same author

Cell-type-aware transcriptome-wide association studies identify 91 independent risk genes for Alzheimer's disease dementia.

Communications biology·2026

Same author

Objectively Measured Daytime Napping Patterns and All-Cause Mortality in Older Adults.

JAMA network open·2026

Same author

Proteome-wide association study of cortical proteins that may provide resilience for late-life disability.

The journals of gerontology. Series A, Biological sciences and medical sciences·2026

Same author

Genetic predisposition to hand grip strength predicts cognitive decline.

Neurobiology of aging·2026

Search research articles

Related Experiment Video

Updated: Feb 9, 2026

Author Spotlight: Exploring Dynamic Neural Changes Associated with Religious Chanting

Author Spotlight: Exploring Dynamic Neural Changes Associated with Religious Chanting

Published on: May 31, 2024

Religious Orders Study and Rush Memory and Aging Project.

David A Bennett^1,2, Aron S Buchman^1,2, Patricia A Boyle^1,3

¹Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.

Journal of Alzheimer'S Disease : JAD

|June 6, 2018

Summary

This summary is machine-generated.

The Religious Orders Study and Rush Memory and Aging Project advance understanding of Alzheimer's disease (AD) by linking neurobiology to clinical outcomes and exploring non-cognitive symptoms. Further research is crucial for developing effective AD treatments and prevention strategies.

Keywords:

Alzheimer’s disease cognitive decline decision making dementia drug discovery epidemiology motor function neuropathology omics

More Related Videos

Modulation of the Neurophysiological Response to Fearful and Stressful Stimuli Through Repetitive Religious Chanting

Modulation of the Neurophysiological Response to Fearful and Stressful Stimuli Through Repetitive Religious Chanting

Published on: November 4, 2021

A Real-world What-Where-When Memory Test

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

Related Experiment Videos

Last Updated: Feb 9, 2026

Author Spotlight: Exploring Dynamic Neural Changes Associated with Religious Chanting

Author Spotlight: Exploring Dynamic Neural Changes Associated with Religious Chanting

Published on: May 31, 2024

Modulation of the Neurophysiological Response to Fearful and Stressful Stimuli Through Repetitive Religious Chanting

Modulation of the Neurophysiological Response to Fearful and Stressful Stimuli Through Repetitive Religious Chanting

Published on: November 4, 2021

A Real-world What-Where-When Memory Test

A Real-world What-Where-When Memory Test

Published on: May 16, 2017

Area of Science:

Gerontology
Neuroscience
Pathology

Background:

The Religious Orders Study and Rush Memory and Aging Project are longitudinal clinical-pathologic cohort studies.
These studies focus on aging and Alzheimer's disease (AD).

Purpose of the Study:

To summarize research progress and findings over the past five years.
To discuss implications for understanding neurodegenerative diseases and inform future research directions.

Main Methods:

Longitudinal clinical evaluations of older adults without dementia.
Organ donation for detailed clinical-pathologic analysis.
Review of findings from the past five years (post-2011).

Main Results:

Summarized findings on the relationship between neurobiology and clinical AD.
Investigated neurobiologic pathways linking risk factors to AD.
Examined non-cognitive AD phenotypes, including motor function and decision-making.
Reported on the development of a novel drug discovery platform.

Conclusions:

Understanding the complexity of aging and AD at multiple levels is essential.
Effective treatments and prevention strategies for cognitive decline and AD dementia require further research.