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Non-invasive measurements of cell surface receptors
Basic Research in Cardiology
|January 1, 1985
Abstract:
None of the current methods for assessing the effects of subtle changes in drug structure on tissue is entirely satisfactory. The observation that 3H-drug molecules emit photons of light when they bind to membrane proteins (called Condensed Phase Radioluminescence) probably represents a significant advance in measuring non-invasively kinetic effects of drugs on beating monolayers of cardiac myocytes. The potential utility of CPR is great.