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Exploring Therapeutic Potential of Nanocarrier Systems Against Breast Cancer

Lalit Kumar1,2, Ashish Baldi3, Shivani Verma2,4

  • 1Faculty of Pharmaceutical Sciences, Department of Pharmaceutics, PCTE Group of Institutes, Ludhiana, Punjab 142021, India.

Pharmaceutical Nanotechnology
|June 6, 2018
PubMed
Abstract

Insights

Nanocarriers offer promising breast cancer treatment by improving drug delivery and targeting tumor cells. Further clinical evaluation is needed for these advanced nanocarrier systems to reach the pharmaceutical market.

Area of Science:

  • Oncology
  • Nanotechnology
  • Pharmaceutical Sciences

Background:

  • Breast cancer is a prevalent cancer in women with limited and toxic treatment options.
  • Nanocarrier-based approaches are being investigated to overcome limitations of current breast cancer therapies.
  • Various nanocarriers, including liposomes, nanoparticles, and dendrimers, are explored for breast cancer treatment.

Purpose of the Study:

  • To review the therapeutic efficacy of diverse nanocarrier systems against breast cancer.
  • To explore the potential of nanocarriers in improving breast cancer treatment outcomes.

Main Methods:

  • A comprehensive literature review was conducted.
  • Databases searched included Pubmed and Google Scholar for relevant studies on nanocarrier systems in breast cancer therapy.

Main Results:

  • Nanocarriers can enhance circulation time and target breast tumors effectively.
  • Both active and passive targeting strategies using nanocarriers can be employed.
  • Targeted nanocarriers show potential in reducing side effects associated with conventional breast cancer treatments.

Conclusions:

  • Multiple nanocarriers demonstrate therapeutic potential in preclinical breast cancer studies.
  • Clinical evaluation and scalable manufacturing are crucial for pharmaceutical market entry.
  • Nanocarrier systems represent a promising advancement in breast cancer therapy.
Keywords:
Active targetingbreast cancerdendrimersnanoliposomesnanoparticlesnon-cutaneous cancer.

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