Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

66.4K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
66.4K
Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

10.5K
The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
10.5K
The Pituitary Gland01:17

The Pituitary Gland

10.9K
The pituitary is a small endocrine organ in the sphenoid bone under the hypothalamus. Primarily, the pituitary in adults has two distinct anatomical and functional regions— the anterior and posterior lobes. During human fetal development, a third pituitary gland region called the pars intermedia atrophies and disappears. However, some of its cells migrate and exist adjacent to the anterior pituitary in adults.
10.9K
Endocrine Signaling01:45

Endocrine Signaling

68.2K
Endocrine cells produce hormones to communicate with remote target cells found in other organs. The hormone reaches these distant areas using the circulatory system. This exposes the whole organism to the hormone but only those cells expressing hormone receptors or target cells are affected. Thus, endocrine signaling induces slow responses from its target cells but these effects also last longer.
68.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In-hospital outcomes of acute coronary syndrome in patients with cancer: a systematic review and meta-analysis.

Journal of cardiovascular medicine (Hagerstown, Md.)·2026
Same author

Substance Use and Motor Vehicle Accident Mortality in the United States: A 22-Year National Analysis.

Substance use & addiction journal·2026
Same author

Trends in Pancreatic Cancer Incidence, Prevalence, and Mortality in the United States and High SDI Countries (1991-2021) and Future Projections: A Forecasting Population-Based Analysis.

Pancreas·2026
Same author

Machine Learning-driven Prediction of Cervical Cancer Cell Viability After Treatment With Thymoquinone, Curcumin, and 5-Fluorouracil.

Applied biochemistry and biotechnology·2026
Same author

Corrigendum to "Trends in gastric surgery operative experience among general surgery residents in the United States: A nationwide retrospective analysis" [Surgery 175 (2024) 1518-1523].

Surgery·2026
Same author

Temporal trends in the incidence, mortality, and prevalence of gallbladder and biliary diseases in high-income countries compared to the USA, 1990 to 2021.

Proceedings (Baylor University. Medical Center)·2026
Same journal

Cerebral Cysticercosis Manifesting 20 Years after Primary Cutaneous Disease.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Primary Leiomyosarcoma of the Pancreas with Liver Metastasis: Challenges and Possible Treatment Approaches.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Rising Trend of Cancer in Pakistan: An Urgent Call for Action.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Conflicting Roles of Urotensin II in Chronic Kidney Disease: Insights from Clinical and Mechanistic Studies.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Invasive Fibromatosis Adjacent to the Twelfth Thoracic Vertebra and Involving the Oesophagus.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
Same journal

Low-Density Lipoprotein Cholesterol Rebound: Rethinking Appendectomy in Coronary Heart Disease.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP·2026
See all related articles

Related Experiment Video

Updated: Feb 9, 2026

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

4.6K

Pituitary Tuberculoma.

Amir Humza Sohail1, Umar Farooq Bhatti2, Najmul Islam3

  • 1Medical College, The Aga Khan University, Karachi.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|June 6, 2018
PubMed
Summary
This summary is machine-generated.

Pituitary tuberculosis is a rare condition, often mimicking pituitary adenoma. This case highlights the importance of histopathology for diagnosing this rare sellar lesion.

More Related Videos

Healthy Brain-pituitary Slices for Electrophysiological Investigations of Pituitary Cells in Teleost Fish
07:14

Healthy Brain-pituitary Slices for Electrophysiological Investigations of Pituitary Cells in Teleost Fish

Published on: August 16, 2018

8.2K
Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells
08:31

Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells

Published on: February 18, 2016

10.5K

Related Experiment Videos

Last Updated: Feb 9, 2026

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology
09:48

Development of Organoids from Mouse Pituitary as In Vitro Model to Explore Pituitary Stem Cell Biology

Published on: February 25, 2022

4.6K
Healthy Brain-pituitary Slices for Electrophysiological Investigations of Pituitary Cells in Teleost Fish
07:14

Healthy Brain-pituitary Slices for Electrophysiological Investigations of Pituitary Cells in Teleost Fish

Published on: August 16, 2018

8.2K
Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells
08:31

Three-dimensional Alginate-bead Culture of Human Pituitary Adenoma Cells

Published on: February 18, 2016

10.5K

Area of Science:

  • Endocrinology
  • Neurology
  • Infectious Diseases

Background:

  • Tuberculosis involvement of the hypothalamo-pituitary region is exceptionally rare, accounting for only 1% of sellar/suprasellar lesions.
  • First reported in 1940, pituitary tuberculosis remains a seldom-encountered clinical entity with limited documented cases.

Observation:

  • A 32-year-old male presented with a 6-month history of headache and declining visual acuity.
  • Ophthalmological examination revealed bitemporal hemianopsia, suggesting optic chiasm compression.
  • Brain MRI demonstrated a sellar mass with imaging characteristics resembling a pituitary adenoma.

Findings:

  • Surgical resection of the sellar mass was performed.
  • Histopathological analysis of the excised tissue confirmed the diagnosis of pituitary tuberculoma.
  • This rare case underscores the diagnostic challenges posed by pituitary tuberculosis.

Implications:

  • Pituitary tuberculoma can present with visual disturbances and hypopituitarism, mimicking more common sellar pathologies.
  • Accurate diagnosis necessitates invasive procedures like trans-sphenoidal biopsy for definitive histopathological confirmation.
  • Increased awareness among clinicians is crucial for timely diagnosis and management of this rare condition.