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A partial fraction is a component of a rational expression represented as the sum of simpler fractions. When a rational function is expressed as a ratio of two polynomials, it can often be decomposed into a sum of fractions whose denominators are simpler polynomials, typically linear or irreducible quadratic factors. This process is called partial fraction decomposition, and it is used to simplify complex expressions for integration, solving equations, or analysis.Partial fraction decomposition...
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Related Experiment Video

Updated: Feb 9, 2026

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure
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Tetanus in a partially immunized child.

Yusuke Akane1, Takeshi Tsugawa1, Tsukasa Hori1

  • 1Department of Pediatrics, Sapporo Medical University School of Medicine, Sapporo, Japan.

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
|June 6, 2018
PubMed
Summary

A vaccinated 13-year-old boy contracted tetanus despite protective antibodies. This case highlights the importance of prompt clinical diagnosis of tetanus, even in vaccinated individuals, especially in developed nations.

Keywords:
ChildPartially immunizedTetanus

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Area of Science:

  • Immunology
  • Infectious Diseases
  • Neurology

Background:

  • Tetanus is a rare but serious bacterial infection caused by Clostridium tetani.
  • Vaccination with tetanus toxoid is highly effective in preventing the disease.
  • Tetanus is characterized by muscle spasms and autonomic nervous system dysfunction.

Observation:

  • A 13-year-old boy presented with symptoms of tetanus, including neck rigidity, diaphoresis, and risus sardonicus.
  • The patient had received three doses of tetanus toxoid vaccine and had protective antitoxin antibody levels.
  • Symptoms appeared four days after an unspecified injury.

Findings:

  • The case demonstrates a rare instance of breakthrough tetanus in a vaccinated individual.
  • Clinical presentation was typical for tetanus, despite documented protective immunity.
  • Prompt diagnosis relied on recognizing characteristic clinical signs and symptoms.

Implications:

  • This case underscores that tetanus vaccination may not always confer complete protection.
  • Physicians must maintain a high index of suspicion for tetanus, even in vaccinated populations.
  • Early clinical diagnosis remains crucial for timely management and improved outcomes in tetanus cases.