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Updated: Feb 9, 2026
07:46
Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa
Published on: October 22, 2015
15.1K
Unusual case of anorexia
Laura Darmaun1, Estelle Aubry2, Sophie Lejeune3
1Department of Pediatrics, Jeanne de Flandres hospital, CHRU Lille, Lille, France.
BMJ Case Reports
|June 6, 2018
Summary
A rare case of colorectal cancer (CRC) in a 15-year-old highlights the need for vigilance. Persistent digestive issues in adolescents warrant thorough investigation to avoid delayed diagnosis of pediatric cancers.
Area of Science:
- Pediatric Oncology
- Gastroenterology
- Surgical Oncology
Background:
- Colorectal cancer (CRC) is exceptionally rare in pediatric and adolescent populations.
- CRC in young individuals is often diagnosed at advanced stages due to low suspicion and atypical presentations.
- This case underscores the diagnostic challenges associated with pediatric gastrointestinal malignancies.
Observation:
- A 15-year-old female presented with anorexia, weight loss, and abdominal pain, initially misdiagnosed as anorexia nervosa.
- The patient developed severe malnutrition and bowel obstruction, leading to the discovery of a transverse colon mass.
- Histological examination confirmed a well-differentiated Lieberkühn adenocarcinoma.
Findings:
- The patient underwent surgical resection (transverse and right colectomy) followed by adjuvant chemotherapy.
- Pediatric CRC cases, regardless of histology or family history, necessitate genetic counseling.
- This case emphasizes the importance of considering rare diagnoses in adolescents with persistent digestive symptoms.
Implications:
- Physicians should maintain a high index of suspicion for colorectal cancer in young patients presenting with recurrent or persistent gastrointestinal symptoms.
- Early and thorough investigation of such symptoms is crucial for timely diagnosis and improved outcomes in pediatric CRC.
- Genetic counseling is recommended for all young patients diagnosed with colorectal cancer to identify potential hereditary syndromes.
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