Related Experiment Video

Updated: Feb 9, 2026

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat
13:50

Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat

Published on: February 5, 2011

81.0K

Pharmacokinetics of Active Components From Guhong Injection in Normal and Pathological Rat Models of Cerebral

Li Yu1, Hao-Fang Wan2, Chang Li1

  • 1College of Life Science, Zhejiang Chinese Medical University, Hangzhou, China.

Frontiers in Pharmacology
|June 6, 2018
PubMed

Keywords:
Guhong injectionHSYAaceglutamidecerebral ischemiacomparisonpharmacokinetics

More Related Videos

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery08:05

A Pre-clinical Rat Model for the Study of Ischemia-reperfusion Injury in Reconstructive Microsurgery

Published on: November 8, 2019

7.9K
Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia10:13

Experimental Models to Study the Neuroprotection of Acidic Postconditioning Against Cerebral Ischemia

Published on: July 31, 2017

8.0K

Related Concept Videos

Normal and Tangetial Components: Problem Solving01:24

Normal and Tangetial Components: Problem Solving

Consider a man with a mass of 70 kg seated in a chair connected to a pin support through a member BC. If the man maintains an upright position, the task is to determine the horizontal and vertical reactions of the chair on the man when the member makes a 45° angle with the horizontal. At this moment, the man has a speed of 5 m/s, increasing at a rate of 1 m/s².
609
Equations of Motion: Normal and Tangetial Components01:10

Equations of Motion: Normal and Tangetial Components

Describing the motion of a particle along a curvilinear path involves understanding its components in terms of normal and tangential aspects. The normal component aligns with the radial direction of the curve at a specific point, reflecting changes in the trajectory of the velocity vector. In contrast, the tangential component is tangential to the curve at that point and signifies the rate at which speed alters along the path.
Newton's second law of motion is employed to articulate the...
1.2K
Curvilinear Motion: Normal and Tangential Components01:27

Curvilinear Motion: Normal and Tangential Components

When a car traverses a curved road, its motion can be elucidated by breaking it down into tangential and normal components. The car-centric coordinates attached to the vehicle move with it.
The positive direction of the t-axis aligns with the increasing position of the car along the curved path, denoted by the unit vector ut. Simultaneously, the n-axis, perpendicular to the t-axis, dissects the curved path into differential arc segments, each forming the arc of a circle with a radius of...
976
Pharmacokinetic Models: Overview01:20

Pharmacokinetic Models: Overview

Pharmacokinetic models utilize mathematical analysis to achieve a detailed quantitative understanding of a drug's life cycle within the body. They are instrumental in simulating a drug's pharmacokinetic parameters, predicting drug concentrations over time, optimizing dosage regimens, linking concentrations with pharmacologic activity, and estimating potential toxicity.
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
2.2K
Nonlinear Pharmacokinetics: Drug Elimination for IV Bolus Injection00:59

Nonlinear Pharmacokinetics: Drug Elimination for IV Bolus Injection

In pharmacokinetics, the elimination rate of a drug following a capacity-limited model is primarily controlled by two parameters: Vmax and KM. These parameters are crucial in how the drug behaves inside the body after administration.
Following the administration of a single intravenous (IV) bolus injection, we can determine the concentration of the drug in the plasma at any given time. This calculation is achieved using a specific equation that integrates the values of Vmax and KM.
We can also...
428
Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
572