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HIV Prevention After Discontinuing Pre-Exposure Prophylaxis: Conclusions From a Case Study
Kai J Jonas1, Natthakhet Yaemim1,2
1Work and Social Psychology, Maastricht University, Maastricht, Netherlands.
Frontiers in Public Health
|June 6, 2018
Summary
Pre-exposure prophylaxis (PrEP) is effective for HIV prevention, but discontinuation requires tailored strategies. Post-PrEP HIV prevention is crucial for individuals discontinuing use, especially those at high risk.
Area of Science:
- Public Health
- Infectious Diseases
- HIV/AIDS Research
Background:
- Pre-exposure prophylaxis (PrEP) using tenofovir disoproxil fumarate and emtricitabine (FTC) is a key HIV prevention method.
- Efforts focus on increasing PrEP access and uptake, particularly among men who have sex with men (MSM).
- PrEP use is not always continuous, with individuals discontinuing use voluntarily or involuntarily.
Observation:
- A case study highlights an MSM individual who seroconverted shortly after discontinuing PrEP due to renal function issues.
- This case illustrates the critical need for post-PrEP HIV prevention strategies.
- Various contexts exist where PrEP discontinuation leads to populations requiring ongoing HIV prevention.
Findings:
- Involuntary PrEP discontinuation coupled with ongoing high HIV risk exposure necessitates specific post-PrEP interventions.
- The knowledge-communication-choice model can inform the development of these strategies.
- Healthcare providers and community organizations must prepare consultation protocols for clients discontinuing PrEP.
Implications:
- Tailored post-PrEP HIV prevention strategies are essential to mitigate HIV risk in vulnerable populations.
- Integrating post-PrEP care into existing HIV prevention services is recommended.
- Proactive planning by healthcare systems can improve outcomes for individuals transitioning off PrEP.
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