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Impact of an 18F-FDG PET/CT Radiotracer Injection Infiltration on Patient Management-A Case Report
Jackson W Kiser1, James R Crowley1, David A Wyatt1
1Carilion Clinic, Roanoke, VA, United States.
Frontiers in Medicine
|June 6, 2018
Summary
Misadministration of 18F-fluorodeoxyglucose (18F-FDG) PET/CT scans can impact cancer diagnosis. A case study shows injection errors led to a repeat scan, revealing distant metastases and altering the treatment plan.
Area of Science:
- Nuclear medicine
- Oncology
- Radiopharmacy
Background:
- 18F-fluorodeoxyglucose (18F-FDG) PET/CT is crucial for managing solid tumors and lymphomas.
- Misadministration of 18F-FDG outside the bloodstream can reduce test sensitivity.
- Such errors are a known, though not infrequent, issue in clinical practice.
Observation:
- A patient undergoing 18F-FDG PET/CT experienced an injection site error.
- This necessitated a repeat PET/CT examination.
- The repeat scan identified previously undetected distant metastases.
Findings:
- The misadministration of 18F-FDG led to the discovery of distant metastases.
- This finding significantly altered the patient's original treatment strategy.
- The case highlights the potential for injection site errors to confound PET/CT interpretation.
Implications:
- Routine monitoring of 18F-FDG injections is recommended, especially when scan sensitivity is critical.
- Injection site errors, or infiltrations, can interfere with the interpretation of semi-quantitative PET metrics.
- Accurate radiotracer administration is vital for reliable oncologic imaging and patient management.
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