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O-cresol Concentration Online Measurement Based On Near Infrared Spectroscopy Via Partial Least Square Regression
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[About a cresol intoxication].

S Fatihi1, P Mols2

  • 1Médecin candidate spécialiste en Médecine aiguë, ULB.

Revue Medicale De Bruxelles
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Summary
This summary is machine-generated.

Cresol ingestion can cause severe systemic toxicity affecting multiple organs. Prompt decontamination and supportive care are crucial for managing phenol poisoning when diagnostic assays are unavailable.

Keywords:
Alkaline poisoningCresol poisoningPhenol poisoning

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Area of Science:

  • Toxicology
  • Emergency Medicine
  • Gastroenterology

Background:

  • Cresols, phenol derivatives, are widely used as disinfectants.
  • Ingestion of cresols can lead to significant local and systemic toxicity.

Observation:

  • A case of a 33-year-old woman who ingested 50-70 cm3 of a 50% cresol solution is presented.
  • Immediate symptoms included coma, bradypnea, and desaturation, necessitating orotracheal intubation.
  • The patient developed caustic lesions, hypotension, ventricular arrhythmias, acute renal failure, and toxic hepatitis within 24 hours.

Findings:

  • Gastroscopy revealed erosive esophagitis and gastroduodenopathy.
  • No routine urine or blood cresol level assays were available.
  • The patient recovered with normalization of liver function after one month.

Implications:

  • Treatment focuses on rapid decontamination and vital function support.
  • Clinical presentation and patient history are essential for diagnosis due to lack of routine assays.
  • This case highlights the severe multi-organ effects of cresol poisoning and the importance of prompt medical intervention.