Repository corticotropin injection in multiple sclerosis: an update.

Area of Science:

• Neurology
• Immunology

Background:

• Relapse management is critical in multiple sclerosis (MS) care.
• Acute MS relapses involve new or worsening neurological symptoms lasting over 24 hours, excluding other causes.

Purpose of the Study:

• To outline current strategies for managing acute multiple sclerosis relapses.
• To highlight alternative treatments for patients with specific needs.

Main Methods:

• Review of established clinical practices for MS relapse treatment.
• Identification of alternative therapies approved by regulatory bodies.

Main Results:

• Corticosteroids, primarily intravenous methylprednisolone, are the standard treatment for MS relapses.
• Repository corticotropin injection is an FDA-approved alternative for specific patient groups.

Conclusions:

• Standard MS relapse treatment relies on corticosteroids.
• Repository corticotropin injection provides a vital alternative for patients with contraindications or poor response to corticosteroids.