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Prostaglandin A2 receptor in rat intestinal basolateral plasma membranes
General Pharmacology
|January 1, 1985
Abstract:
The specific prostaglandin A2 receptor was presented in rat intestinal basolateral plasma membrane. The dissociation constant was 4.39 X 10(-8) M and the value of the binding capacity was 3.33 pmol/mg protein. [3H]prostaglandin A2 binding was specifically inhibited by Na+ or ATP. The inhibition manners of Na+ and ATP for [3H]prostaglandin A2 binding were of a competitive and noncompetitive type, respectively.