Related Experiment Video
Updated: Feb 9, 2026
06:52
Using Cholesky Decomposition to Explore Individual Differences in Longitudinal Relations between Reading Skills
Published on: September 17, 2019
6.8K
Piracetam in developmental reading disorders: A review
Colin R Wilsher1,2, Eric A Taylor3
1College Visiting Fellow, Department of Psychology, University College of North Wales, UK.
European Child & Adolescent Psychiatry
|June 7, 2018
Summary
Piracetam, a nootropic drug, showed statistical superiority over placebo in treating developmental reading disorder in children. While the effect is modest, it is well-tolerated and promising for future therapeutic applications.
Area of Science:
- Neuroscience
- Pharmacology
- Developmental Psychology
Background:
- Developmental reading disorder (DRD) affects numerous children globally.
- Nootropic drugs are explored for cognitive enhancement and neurological disorders.
- Piracetam is the pioneering nootropic agent investigated for therapeutic potential.
Purpose of the Study:
- To review existing studies on piracetam for treating developmental reading disorder.
- To assess the efficacy and safety of piracetam in pediatric populations with DRD.
- To evaluate the clinical significance and mechanism of action of piracetam in this context.
Main Methods:
- Systematic review and meta-analysis of controlled double-blind trials.
- Inclusion of studies with 751 children completing piracetam treatment.
- Standardized reading tests used as primary outcome measures.
Main Results:
- Quantitative and qualitative review indicates piracetam's statistical superiority to placebo.
- Piracetam was found to be well-tolerated among child participants.
- A modest effect size was observed, with a favorable benefit-hazard balance.
Conclusions:
- Piracetam demonstrates efficacy as a treatment for developmental reading disorder.
- The drug's favorable safety profile supports its consideration for clinical use.
- Further research into piracetam's mechanism and long-term effects is warranted.
More Related Videos
06:16Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
Published on: June 6, 2020
4.6K
06:33Decomposing the Variance in Reading Comprehension to Reveal the Unique and Common Effects of Language and Decoding
Published on: October 11, 2018
7.2K
Related Concept Videos
01:10Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
01:13Review and Preview
11.5K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.5K
02:46Uncertainty in Measurement: Reading Instruments
53.3K
Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
53.3K
01:27Introduction to Developmental Psychology
1.6K
Developmental psychology explores the changes and continuities in human abilities throughout life, encompassing physical, cognitive, linguistic, and social dimensions. Human development is not restricted to growth, but includes aspects of decline, particularly in physical abilities as individuals age. Developmental psychologists seek to understand how people change as they age and how their mental and social skills evolve.Developmental MilestonesA key concept in developmental psychology is...
1.6K
01:29Three Developmental Domains
1.2K
Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
1.2K
02:18Intrinsically Disordered Proteins
19.6K
Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...
19.6K