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Strongyloides species infestation in young infants of papu, New Guinea: association with generalized oedema
Papua and New Guinea Medical Journal
|January 1, 1979
Insights
Swollen Belly Sickness in infants is linked to Strongyloides infection. Proposed treatment includes thiabendazole, plasma transfusions, and antibiotics for this serious condition.
Area of Science:
- Pediatric Medicine
- Infectious Diseases
- Gastroenterology
Background:
- Infants can present with severe symptoms including abdominal distension, respiratory distress, and edema.
- Gastrointestinal dysfunction is a common feature in affected infants.
Observation:
- Analysis of thirteen infants revealed a distinct clinical syndrome termed "Swollen Belly Sickness."
- A strong association was identified between this syndrome and infection with Strongyloides species.
Findings:
- The causative Strongyloides species closely resembles Strongyloides fulleborni.
- A multi-modal treatment approach is proposed, including specific antiparasitic medication, supportive care, and antibiotics.
Implications:
- This research highlights a critical link between parasitic infection and a severe infant illness.
- The proposed treatment offers a potential therapeutic strategy for Swollen Belly Sickness, improving infant outcomes.
Abstract:
Clinical and laboratory details of thirteen infants with "Swollen Belly Sickness" who has abdominal distension, respiratory distress, generalised oedema, and variable disturbance of gastrointestinal function were analysed. The intimate connection between the syndrome and infection with Strongyloides species closely resembling Strongyloides fulleborni - is discussed, and a standard treatment using thiabendazole, plasma transfusion and antibiotics, is proposed.