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Chronic Salmonella Infection Induced Intestinal Fibrosis
Published on: September 22, 2019
[Inflammatory bowel diseases : Crohn's disease and ulcerative colitis]
S Fischer1, T Rath2, M F Neurath2
1Medizinische Klinik 1, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Ulmenweg 18, 91054, Erlangen, Deutschland. sarah.fischer@uk-erlangen.de.
Der Internist
|June 7, 2018
Summary
Inflammatory bowel diseases (IBD) involve chronic digestive issues. Early diagnosis and treatment, including anti-inflammatory and immunosuppressive therapies, are crucial for managing IBD and its complications.
Area of Science:
- Gastroenterology
- Immunology
- Epidemiology
Background:
- Inflammatory bowel diseases (IBD) represent a growing global health concern, particularly in industrialized nations.
- IBD are chronic conditions characterized by symptoms such as persistent diarrhea, abdominal pain, and rectal bleeding.
- These diseases can also lead to extraintestinal manifestations affecting joints, skin, eyes, and bile tracts.
Purpose of the Study:
- To provide an overview of Inflammatory Bowel Diseases (IBD).
- To summarize current diagnostic and therapeutic approaches for IBD based on literature and guidelines.
- To emphasize the importance of early intervention and interdisciplinary care in managing IBD.
Main Methods:
- Literature search conducted in PubMed.
- Analysis oriented on current European Crohn's and Colitis Organisation guidelines.
- Synthesis of information on IBD characteristics, manifestations, and treatments.
Main Results:
- IBD are complex chronic conditions with increasing incidence.
- Key symptoms include chronic diarrhea, abdominal pain, and peranal hemorrhage.
- Treatment involves aminosalicylates, corticosteroids, thiopurines, calcineurin inhibitors, and biologicals, requiring anti-inflammatory and immunosuppressive strategies.
Conclusions:
- Early diagnosis and intervention significantly impact patient outcomes in IBD.
- Management of IBD necessitates a comprehensive approach addressing both intestinal and extraintestinal complications.
- An interdisciplinary team is essential for optimal patient care, potentially including surgical intervention.
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