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Marfan Syndrome: oral implication and management.
P Bollero1, L Arcuri2, M Miranda1
1Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.
ORAL & Implantology
|June 8, 2018
Summary
Marfan syndrome, a genetic connective tissue disorder, affects multiple body systems. This review details oral manifestations and dental management strategies for patients with this condition.
Area of Science:
- Genetics and Molecular Biology
- Pathology
- Dentistry
Background:
- Marfan syndrome is an autosomal dominant inherited connective tissue disorder.
- It results from mutations in the FBN1 gene, encoding fibrillin-1, or less commonly, the TGFBR2 gene.
- The condition presents with diverse clinical manifestations affecting various organs.
Purpose of the Study:
- To review the oral cavity manifestations of Marfan syndrome.
- To outline appropriate patient management during dental procedures.
Main Methods:
- Literature review of scientific articles and case reports.
- Analysis of clinical findings related to oral health in Marfan syndrome patients.
Main Results:
- Common oral findings include high-arched palate, dental crowding, and temporomandibular joint issues.
- Patients may exhibit increased risk for certain dental complications.
Conclusions:
- Early recognition of oral signs is crucial for comprehensive Marfan syndrome care.
- Tailored dental management plans are essential for affected individuals.
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