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Related Experiment Video

Updated: Feb 9, 2026

Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos

Phage Therapy Application to Counteract Pseudomonas aeruginosa Infection in Cystic Fibrosis Zebrafish Embryos

Published on: May 12, 2020

Phage Therapy: Beyond Antibacterial Action.

Andrzej Górski^1,2,3, Ewa Jończyk-Matysiak¹, Ryszard Międzybrodzki^1,2,3

¹Bacteriophage Laboratory, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław, Poland.

Frontiers in Medicine

|June 8, 2018

Summary

Bacteriophages, or phages, are viruses that infect bacteria. Recent research reveals phages may interact with eukaryotic cells, opening new therapeutic possibilities beyond combating antimicrobial resistance.

Keywords:

immunomodulation inflammation phage phage therapy prophage induction

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Published on: January 2, 2017

Area of Science:

Microbiology
Virology
Biotechnology

Background:

Phages were traditionally viewed solely as antibacterial agents.
Antimicrobial resistance necessitates novel therapeutic strategies.
Emerging research suggests broader biological roles for phages.

Purpose of the Study:

To explore the significance of phages beyond their antibacterial properties.
To discuss the potential of phage-host interactions with eukaryotic cells.
To evaluate the translation of these interactions into medical advancements.

Main Methods:

Review of current phage biology research.
Analysis of accumulating data on phage-eukaryotic cell interactions.
Discussion of potential therapeutic applications.

Main Results:

Phages possess functions beyond bacterial lysis.
Evidence suggests phages interact with eukaryotic cells.
These interactions present novel therapeutic avenues.

Conclusions:

Phage biology research is expanding our understanding of their roles.
Phage-eukaryotic cell interactions offer promising therapeutic potential.
Further investigation is crucial for developing new medical treatments.