Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Growth of Cartilage and Bone Tissue

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

Meristems and Plant Growth

Meristems and Plant Growth

Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.

Population Growth

Population Growth

Population size is dynamic, increasing with birth rates and immigration, and decreasing with death rates and emigration. In ideal conditions with unlimited resources, populations can increase exponentially, which plots as a J-shaped growth rate curve of population size against time. This type of curve is characteristic of newly-introduced invasive species, or populations that have suffered catastrophic declines and are rebounding.

Primary and Secondary Growth in Roots and Shoots

Primary and Secondary Growth in Roots and Shoots

Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.

Relationship Growth

Relationship Growth

Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...

Exponential Growth

Exponential Growth

Bacterial populations exhibit exponential growth when conditions such as nutrient availability and temperature are favorable. In this phase, cells reproduce through binary fission, where each cell divides into two identical daughter cells. This process causes the population to double at regular intervals, resulting in a growth rate that is directly proportional to the current number of cells. As the population increases, the number of new cells formed during each generation also grows, creating...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Reduced paraspinal muscle endurance and electromyographic fatigability are associated with greater global spinal imbalance in symptomatic lumbar spinal stenosis.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·2026

Same author

Critical velocity metric derived from dynamic finite element analysis classifies hip fracture risk in a clinical cohort.

Journal of biomechanics·2026

Same author

Ex vivo mechanical evaluation of anatomically and mechanically conforming patient-specific lumbar spinal fusion cages designed by full-scale topology optimization.

North American Spine Society journal·2026

Same author

DXA-derived biofidelic finite element models for quantifying the efficacy of hip protectors.

JBMR plus·2026

Same author

Characterization of the acetabular labrum articular surface and its translation into biomimetic graft design.

Frontiers in bioengineering and biotechnology·2026

Same author

Motion capture dataset of 137 post-operative total hip replacement patients performing activities of daily living.

Scientific data·2026

Search research articles

Related Experiment Video

Updated: Feb 9, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

Simulated tissue growth for 3D printed scaffolds.

Paul F Egan¹, Kristina A Shea², Stephen J Ferguson²

¹ETH Zurich, Zurich, Switzerland. paul.egan.phd@gmail.com.

Biomechanics and Modeling in Mechanobiology

|June 8, 2018

Summary

Biological tissue growth depends on scaffold geometry. Simulations reveal optimal lattice designs balance curvature sensing and permeability for faster tissue infill in regenerative medicine applications.

More Related Videos

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

Related Experiment Videos

Last Updated: Feb 9, 2026

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Multimodal 3D Printing of Phantoms to Simulate Biological Tissue

Published on: January 11, 2020

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

Area of Science:

Biomaterials Science
Tissue Engineering
Computational Biology

Background:

Biological tissues exhibit mechanical sensing of localized curvature, influencing growth patterns.
Scaffold geometry is a critical factor in designing effective tissue engineering constructs.
Understanding tissue growth dynamics on complex surfaces is essential for clinical applications.

Purpose of the Study:

To develop a simulation approach for modeling tissue growth on beam-based scaffold geometries.
To investigate the impact of lattice topology on tissue growth rates and patterns.
To identify optimal scaffold designs that balance conflicting factors like growth speed and permeability.

Main Methods:

Developed a simulation model for tissue growth on repeating unit cell geometries.
Analyzed four distinct lattice topologies under fixed and variable geometric constraints.
Quantified tissue growth based on positive curvature and scaffold permeability.

Main Results:

Tissue growth preferentially occurred in voxels with positive curvature.
Growth rates varied with lattice topology, influenced by beam density and porosity.
Scaffolds with lower permeability showed faster tissue filling, impacting nutrient transport.
Optimal trade-offs were identified for scaffolds with specific beam diameters and porosity.

Conclusions:

Scaffold geometry significantly influences curvature-driven tissue growth.
Lattice topology and porosity are key parameters for optimizing tissue scaffold design.
Findings provide a foundation for developing advanced scaffolds for tissue regeneration.