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Updated: Feb 9, 2026

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
Published on: November 20, 2015
Changes in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery
Cara Bohon1, Luis C Garcia2, John M Morton1
1School of Medicine, Section of Bariatric and Minimally Invasive Surgery, Stanford University, 900 Blake Wilbur Drive, Room W0048, Stanford, CA, 94305, USA.
Abstract:
Cerebral cortical thickness is associated with memory and intelligence test scores and serves as a measure for changes in cortical gray matter. Previous studies suggest reduced cortical thickness in patients with obesity. This study aimed to investigate changes in cortical thickness following bariatric surgery. Magnetic resonance imaging (MRI) data of five patients were analyzed preoperatively and 6 months postoperatively to assess changes in global measures of cortical thickness. No patients were lost to follow-up. This study provides preliminary evidence of brain change following surgery, suggests increases in cerebral cortical thickness in patients with greater excess weight loss, and indicates the need for further investigation using larger samples and correlation with neurocognitive measures, such as memory recall.
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