Silica-Coated Magnetite Nanoparticles Carrying a High-Density Polymer Brush Shell of Hydrophilic Polymer

Integrating the properties of magnetite nanoparticles (MNPs) and high-density polymer brushes in one structure requires sophisticated synthetic designs and effective chemical approaches. A simple and versatile strategy for the fabrication of hydrophilic-polymer-capped magnetite-core-silica-shell nanohybrids with well-defined structure employing reverse microemulsion technique and reversible addition-fragmentation chain transfer (RAFT) polymerization is presented. The high-density polymer brush allows precise patterning of the magnetic nanohybrids with a tunable interparticle distance ranging from 20 nm to 80 nm by controlling the polymer size. The high structural precision provides a near stand-alone state of the MNPs in the nanohybrids with effectively inhibited magnetic interaction, as shown by superconducting quantum interference device (SQUID) measurements.