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Updated: Feb 9, 2026

Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve
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Triple valve surgery: results from a multicenter experience.

Alessandro Leone1, Daniela Fortuna2, Davide Gabbieri3

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|June 8, 2018
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Triple valve surgery (TVS) shows acceptable early and mid-term outcomes, but carries risks. Renal failure, reoperations, and coronary artery bypass grafting (CABG) are significant predictors of mortality in TVS patients.

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Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Cardiac Valve Repair and Replacement

Background:

  • Triple valve surgery (TVS) remains a complex procedure in cardiac surgery.
  • TVS is associated with significant mortality and morbidity rates.
  • Evaluating early and mid-term outcomes of TVS is crucial for patient management.

Purpose of the Study:

  • To retrospectively analyze patient data from the RERIC registry.
  • To evaluate the early and mid-term results of triple valve surgery (TVS).
  • To identify predictors of mortality and adverse outcomes in TVS patients.

Main Methods:

  • Data from 44,211 cardiac surgical procedures were collected from April 2002 to December 2013.
  • 280 patients undergoing TVS were identified and categorized by procedure type.
  • Univariate and multivariate analyses were performed to determine mortality predictors.

Main Results:

  • The in-hospital mortality rate for TVS was 7.9%, with tricuspid valve replacement having the highest mortality (40%).
  • Independent predictors of in-hospital mortality included elevated serum creatinine, concomitant coronary artery bypass grafting (CABG), and prior cardiac surgery.
  • Cumulative mortality at 1, 3, and 5 years was 14.7%, 24.1%, and 28.9%, respectively.

Conclusions:

  • Triple valve surgery (TVS) demonstrated satisfactory in-hospital and mid-term mortality rates.
  • Renal failure, reoperations, and concomitant CABG were identified as risk factors for mortality.
  • No significant mid-term survival benefit of mitral valve repair over replacement was observed.