Session 1: Colon cancer - 10 years behind the rectum

V Tudyka1, R Madoff2, A Wale1

  • 1Royal Marsden NHS Foundation Trust, London, UK.

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This lesson provides an in-depth discussion of the stereochemical outcomes in an SN1 reaction.
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SN1 Reaction: Kinetics02:05

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Acidity of 1-Alkynes02:42

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The acidic strength of hydrocarbons follows the order: Alkynes > Alkenes > Alkanes. The strength of an acid is commonly expressed in units of pKa — the lower the pKa, the stronger the acid. Among the hydrocarbons, terminal alkynes have lower pKa values and are, therefore, more acidic. For example, the pKa values for ethane, ethene, and acetylene are 51, 44, and 25, respectively, as shown here.
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