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Related Concept Videos

Spinal Cord01:26

Spinal Cord

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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The Spinal Cord01:54

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Spinal Cord: Information Processing01:10

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The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
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Spinal Cord: Gross Anatomy01:15

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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
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Spinal Cord: Cross-sectional Anatomy01:16

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
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Antipsychotic drugs are classified into first-generation (typical) drugs including phenothiazines; and second-generation (atypical) drugs. Chlorpromazine hydrochloride (Thorazine), a phenothiazine derivative, broadly impacts the central, autonomic, and endocrine systems. This drug, along with typical agents like haloperidol (Haldol), primarily works by antagonizing D2 receptors, thus reducing dopaminergic neurotransmission. However, typical antipsychotics can cause side effects such as sedation...
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Acute and Chronic Tactile Sensory Testing after Spinal Cord Injury in Rats
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Atypical spinal cord infarction: A case report.

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Acute spinal cord infarction (SCI) presents as a neurologic emergency. Diffusion-weighted MRI (DWI) with ADC maps aids early diagnosis, distinguishing SCI from other conditions for better patient outcomes.

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Area of Science:

  • Neurology
  • Radiology
  • Emergency Medicine

Background:

  • Acute onset of sensorimotor deficits necessitates urgent medical evaluation.
  • Spinal cord infarction (SCI) is a rare but critical condition causing sudden quadriplegia or quadriparesis.
  • Magnetic resonance imaging (MRI) is crucial for diagnosing SCI.

Observation:

  • A 75-year-old male with comorbidities presented with sudden quadriplegia.
  • Diffusion-weighted contrast MRI (DWI) revealed characteristic signal abnormalities in the grey matter.
  • Initial treatment with steroids for suspected myelitis was ineffective.

Findings:

  • Spontaneous SCI was diagnosed via exclusion.
  • MRI findings included hyperintense signals on DWI and decreased ADC values.
  • The combination of DWI and ADC maps is key for accurate diagnosis.

Implications:

  • Early diagnosis of SCI is critical for timely management.
  • MRI with DWI and ADC mapping should be considered in suspected cases of acute SCI.
  • Distinguishing SCI from other neurological disorders is essential for appropriate treatment and rehabilitation planning.