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Cohort profile: the Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN)

Maria Wanitschek1, Michael Edlinger2, Jakob Dörler1

  • 1University Clinic of Internal Medicine III - Cardiology and Angiology, Medical University of Innsbruck, Innsbruck, Austria.

BMJ Open
|June 9, 2018
PubMed

Insights

The CARDIIGAN cohort study investigates cardiovascular risk factors in patients undergoing coronary angiography. It aims to improve understanding of coronary artery disease diagnosis, severity, and long-term prognosis.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • The Coronary Artery disease Risk Determination In Innsbruck by diaGnostic ANgiography (CARDIIGAN) cohort was established to investigate cardiovascular health.
  • It focuses on patients referred for elective coronary angiography, a key diagnostic procedure.

Purpose of the Study:

  • To enhance understanding of cardiovascular risk factors.
  • To explore the relationship between risk factors and the diagnosis and severity of coronary artery disease (CAD).
  • To analyze the long-term prognosis of patients with CAD.

Main Methods:

  • The study enrolled 8296 patients (aged 18-91 years, 65% male) at the University Clinic of Cardiology, Innsbruck, between February 2004 and April 2008.
  • Follow-up data on vital status were collected via record linkage for 84% of the cohort, with a follow-up duration of 5.5 to nearly 10.0 years.
  • Data collected include patient characteristics, risk factors, lab results, medications, CAD details, revascularization history, treatment, and mortality.

Main Results:

  • Initial analyses have been published, with ongoing studies planned.
  • The cohort provides a rich dataset for exploring various aspects of cardiovascular health and disease.
  • Long-term prognosis and patient outcomes are key areas of investigation.

Conclusions:

  • The CARDIIGAN cohort is a valuable resource for studying coronary artery disease and cardiovascular risk.
  • Further research will focus on diagnostic and prognostic aspects, including complications and cost-effectiveness.
  • Collaboration is encouraged to maximize the research potential of this cohort.
Abstract

Keywords:
cardiovascular risk factorsclinical epidemiologycohort studycoronary artery diseaseelective cardiac catheterisation

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