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Retinopathy of prematurity: preferred practice patterns among pediatric ophthalmologists

Samiksha Fouzdar Jain1, Helen H Song2, Shaza N Al-Holou2

  • 1Ophthalmology Department, Children's Hospital and Medical Center, Omaha, NE, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|June 9, 2018
PubMed

Insights

Pediatric ophthalmologists worldwide prefer laser treatment for retinopathy of prematurity (ROP). While bevacizumab is used, laser therapy is more common due to safety concerns with bevacizumab (IVB).

Area of Science:

  • Ophthalmology
  • Neonatal Care
  • Medical Practice

Background:

  • Retinopathy of prematurity (ROP) treatment lacks standardization globally.
  • Significant variations exist in ROP management approaches among healthcare providers.

Purpose of the Study:

  • To identify preferred ROP treatment practices by surveying pediatric ophthalmologists worldwide.
  • To determine the preferred first-line therapy for ROP.
  • To assess preferred intravitreal bevacizumab (IVB) dosages and outcomes.

Main Methods:

  • An anonymous 18-question online survey was distributed to an international pediatric ophthalmology interest group in early 2017.
  • The survey focused on preferred ROP treatments, IVB dosage, and associated complications.

Main Results:

  • 71.8% of surveyed ophthalmologists treat ROP.
  • 68.3% prefer laser treatment over bevacizumab for type 1 ROP; 32.7% prefer bevacizumab.
  • Laser treatment success rates were reported between 75%-100% by 92.1% of respondents.

Conclusions:

  • Laser photoablation is the predominant treatment choice for ROP globally.
  • Bevacizumab use is less common due to concerns regarding its safety profile and long-term effects.
  • No endophthalmitis cases were reported following intravitreal bevacizumab injections.
Abstract

Keywords:
intravitreal bevacizumablaser photoablationneonatal intensive care unitretinopathy of prematurity

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