Related Experiment Video
Updated: Feb 9, 2026

Application of Design Aspects in Uniaxial Loading Machine Development
Published on: September 19, 2018
Betaine in Inflammation: Mechanistic Aspects and Applications
Guangfu Zhao1, Fang He1, Chenlu Wu1
1College of Animal Science and Technology, Southwest University, Chongqing, China.
Abstract:
Betaine is known as trimethylglycine and is widely distributed in animals, plants, and microorganisms. Betaine is known to function physiologically as an important osmoprotectant and methyl group donor. Accumulating evidence has shown that betaine has anti-inflammatory functions in numerous diseases. Mechanistically, betaine ameliorates sulfur amino acid metabolism against oxidative stress, inhibits nuclear factor-κB activity and NLRP3 inflammasome activation, regulates energy metabolism, and mitigates endoplasmic reticulum stress and apoptosis. Consequently, betaine has beneficial actions in several human diseases, such as obesity, diabetes, cancer, and Alzheimer's disease.
Related Concept Videos
Inflammation
Mechanistic Models: Overview of Compartment Models
Quantitative Aspects of Drug-Receptor Interaction
Mechanistic Models: Compartment Models in Individual and Population Analysis
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Photoluminescence: Applications

