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[Alveolar microlithiasis: about a new case]
Nahid Zaghba1, Kawtar El Hachimi1, Hanane Benjelloun1
1Service des Maladies Respiratoires, CHU Ibn Rochd, Casablanca, Maroc.
The Pan African Medical Journal
|June 9, 2018
Summary
Alveolar microlithiasis (AM) is a rare lung disease involving calcium buildup. This case highlights its characteristic imaging findings and genetic links.
Area of Science:
- Pulmonary Medicine
- Radiology
- Genetics
Background:
- Alveolar microlithiasis (AM) is a rare pulmonary disease.
- Characterized by calcium concretions in alveolar spaces.
- Etiology remains largely unknown.
Observation:
- A case of AM was diagnosed.
- Initial suspicion arose from chest X-ray findings.
- Chest CT scan and transbronchial biopsy confirmed the diagnosis.
Findings:
- Imaging findings were pathognomonic for AM.
- The disease can be asymptomatic despite significant radiographic changes.
- Autosomal recessive inheritance is suspected, linked to SLC34A2 gene mutations.
Implications:
- Highlights the importance of imaging in diagnosing rare lung diseases.
- Suggests a genetic basis for Alveolar Microlithiasis.
- Further research into SLC34A2 mutations may elucidate disease mechanisms.
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