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Updated: Feb 9, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
No risk reduction for Plasmodium vivax malaria in sickle cell disease
1Section of Hematology and Transfusion Medicine, Pathology and Laboratory Medicine The Aga Khan University Karachi Pakistan.
Abstract:
Hemoglobin S is known to protect against uncomplicated Plasmodium falciparum malaria. However, there is paucity of the literature regarding interaction of HbS and other malaria species. Usually, P. vivax malaria is a relapsing condition, and without radical cure with primaquine, recurrence may be observed even with hemoglobin S.
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