Reconstruction of continuous brachial artery pressure wave from continuous finger arterial pressure in humans

Generalized transfer functions (GTFs) are available to compute the more relevant proximal blood pressure (BP) waveform from a more easily measured peripheral BP waveform. However, GTFs are based on the black box model. This paper presents a practical approach to reconstruct brachial artery pressure (BAP) distally from finger artery pressure (FAP). We assume that continuous BAP can be simply approximated by summing two halves of the continuous FAP shifted by the time delay. We firstly showed that the pressure wave in the finger artery can be considered twice as much as the forward/backward wave in the finger. A simplified individualized transfer function was then derived so as to estimate BAP from FAP. The effectiveness of the method was examined by experiment involving 26 healthy volunteers (26.7 ± 3.8 years old) in a resting state. By comparing with a reference BAP, we found that the proposed method can correct the FAP. The errors of the proposed method in estimating systolic and diastolic pressures are - 0.6 ± 6.0 and - 0.6 ± 3.7 mmHg, respectively. These results agree with the standard of Association for the Advancement of Medical Instrumentation (AAMI). We also found that the reconstructed BAP from FAP by terminal arterial occlusion technology (TAOT) is comparable to that of the artery occlusion technology (AOT). Our method or TAOT is promising in estimating continuous proximal blood pressure from peripheral blood pressure in practice.