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[What rheumatologists can learn from ophthalmologists].

M D Becker1,2, R Max3, A Dimitriou4

  • 1Augenklinik, Stadtspital Triemli, Birmensdorfer Str. 497, 8063, Zürich, Schweiz. Matthias.Becker@triemli.zuerich.ch.

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|June 9, 2018
PubMed
Summary

Uveitis, a common cause of blindness, presents diagnostic and treatment challenges. This article explores its broad spectrum and interdisciplinary management, particularly the interface between rheumatology and ophthalmology.

Keywords:
DiagnosticsImmunosuppressionInterdisciplinary cooperationSystemic diseasesUveitis

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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Uveitis, a complex intraocular inflammation, poses significant diagnostic and therapeutic challenges in ophthalmology.
  • It is a leading cause of blindness globally, with costs comparable to diabetic retinopathy.
  • Uveitis affects all ages, can manifest in any part of the eye, and presents with diverse symptoms, from asymptomatic cases to severe pain and vision loss.

Purpose of the Study:

  • To discuss the diagnostic and therapeutic challenges of uveitis.
  • To highlight the broad differential diagnoses, including infectious and systemic causes.
  • To explore the interdisciplinary management of non-infectious uveitis, integrating rheumatological and ophthalmological approaches.

Main Methods:

  • Review of current diagnostic and therapeutic strategies for uveitis.
  • Discussion of the interface between rheumatology and ophthalmology in managing uveitis.
  • Analysis of systemic conditions associated with uveitis, such as ankylosing spondylitis and sarcoidosis.

Main Results:

  • Uveitis encompasses a wide range of conditions with varied presentations and courses (unilateral, bilateral, relapsing, chronic).
  • Differential diagnoses are extensive, including infectious etiologies and ocular manifestations of systemic diseases.
  • Immunosuppressive treatments commonly used in rheumatology are applicable to non-infectious uveitis, alongside local and regional therapies.

Conclusions:

  • Effective management of uveitis requires an interdisciplinary approach, bridging ophthalmology and rheumatology.
  • Understanding the systemic connections of uveitis is crucial for accurate diagnosis and comprehensive treatment.
  • Further exploration of diagnostic and therapeutic impulses at this interdisciplinary interface is warranted.