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Updated: Feb 9, 2026

Detection of Histone Modifications in Plant Leaves
Published on: September 23, 2011
Oligoamide, a new lactam from the leaves of Angylocalyx oligophyllus
Brussine Nadège Wakeu Kweka1,2, Jean-Bosco Jouda1, Gertrude Foudjo Melacheu1
1a Department of Organic Chemistry, Faculty of Science , University of Yaoundé I , Yaoundé , Cameroon.
Abstract:
A new lactam, oligoamide (1), along with three known compounds (2-4), stigmasterol-3-O-β-D-glucopyranoside (2), formononetin (3) and (-)-pinitol (4) were isolated from the CH2Cl2/CH3OH (1:1) extract of the leaves of Angylocalyx oligophyllus by chromatographic separation. Their structures were elucidated on the basis of spectroscopic analysis (UV, IR, MS, 1D, and 2D NMR). Compound 1 was found to have weak antioxidant and urease inhibitory potential.
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Leaving Groups
In general, in a nucleophilic substitution reaction, a nucleophile displaces a functional group, called the leaving group, from the substrate to give a substituted product. A leaving group departs the substrate molecule through heterolytic cleavage, taking the pair of electrons with it to become a relatively stable weak base in the form of an anion or a neutral molecule.
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