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Updated: Feb 9, 2026

Chronic, Acute, and Reactivated HIV Infection in Humanized Immunodeficient Mouse Models
Published on: December 3, 2019
HIV testing in Acute Care
1Consultant in Infectious Diseases and General Internal Medicine, Manchester University Foundation Trust, Cobbett House, Manchester Royal Infirmary, Oxford Rd, Manchester M13 9WL, UK.
Abstract:
Readers may be aware of the need to improve uptake of HIV testing in health care-settings to reduce the number of individuals with undiagnosed infection who later present with advanced disease. Late presentation of HIV infection is associated with a poorer immune response to antiretroviral therapy, an increased morbidity and mortality with a resultant higher cost burden to health-care services. Individuals with undiagnosed HIV infection who inadvertently transmit their infection to others are thought to be responsible for more than half of new HIV infections in the USA.
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