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Omnipotent phosphorene: a next-generation, two-dimensional nanoplatform for multidisciplinary biomedical applications
Meng Qiu1, Wen Xiu Ren, Taeho Jeong
1Department of Chemistry, Korea University, Seoul 02841, Korea. jongskim@korea.ac.kr.
Chemical Society Reviews
|June 9, 2018
Summary
Few-layer black phosphorus (FLBP) shows promise in biomedicine, offering advanced cancer diagnosis and therapy. Its unique properties enable efficient drug delivery and imaging, highlighting its multidisciplinary potential.
Area of Science:
- Materials Science
- Nanotechnology
- Biomedical Engineering
Background:
- Phosphorene, or few-layer black phosphorus (FLBP), is a novel 2D material with unique physicochemical properties.
- FLBP exhibits excellent biocompatibility, making it suitable for various biomedical applications.
- Its intrinsic fluorescence and photoacoustic properties position it as a potential cancer diagnostic agent.
Purpose of the Study:
- To review the latest advancements in FLBP-based nanoplatforms for biomedical applications.
- To highlight the multidisciplinary potential of FLBP in diagnostics, therapy, and drug delivery.
- To provide an overview of FLBP's unique properties and their translation into nanomedicine.
Main Methods:
- Review of recent literature on FLBP nanomaterials in biomedicine.
- Analysis of FLBP's optical, physical, and chemical properties relevant to biomedical use.
- Synthesis and characterization of FLBP for various applications.
Main Results:
- FLBP demonstrates potential for cancer diagnosis via fluorescence and photoacoustic imaging with low cytotoxicity.
- FLBP-based therapies show high anti-tumor efficacy through photothermal and photodynamic mechanisms.
- FLBP serves as an effective drug delivery platform due to its high drug-loading capacity and tunable structure.
Conclusions:
- FLBP nanomaterials offer significant advantages for multidisciplinary biomedical applications.
- FLBP is a versatile platform for advanced cancer diagnosis, therapy, and drug delivery.
- Further research into FLBP-based nanoplatforms is warranted to fully exploit their therapeutic and diagnostic potential.
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