Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The sensitive period.

G K von Noorden, M L Crawford

    Transactions of the Ophthalmological Societies of the United Kingdom
    |January 1, 1979
    PubMed
    Summary

    Visual deprivation during sensitive periods causes functional reorganization, not arrested development. The brain remains adaptable to visual input even after maturation, allowing for reversal of effects.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Optokinetic asynunetry in esotropia.

    Journal of pediatric ophthalmology and strabismus·2014
    Same author

    Recurrent esotropia.

    Journal of pediatric ophthalmology and strabismus·2014
    Same author

    The development of the art and science of strabismology outside North America: Part II.

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2001
    Same author

    The development of the art and science of strabismology outside North America: part I.

    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2001
    Same author

    Experimental glaucoma in primates: changes in cytochrome oxidase blobs in V1 cortex.

    Investigative ophthalmology & visual science·2001
    Same author

    Orthotropia not an oxymoron.

    Binocular vision & strabismus quarterly·2000

    Area of Science:

    • Neuroscience
    • Developmental Biology
    • Ophthalmology

    Background:

    • A sensitive period exists for visual function development, influenced by visual stimulation.
    • Visual deprivation during this period can lead to specific syndromes with varying effects at different brain levels.

    Purpose of the Study:

    • To investigate the timing and nature of visual deprivation effects on the developing visual system.
    • To explore the potential for functional reorganization and reversal of visual deprivation effects.

    Main Methods:

    • Experiments in monkeys involving visual deprivation and reverse suturing.
    • Analysis of behavioral, electrophysiological, and histological changes.
    • Comparison of effects at cortical and geniculate levels.

    Main Results:

    • Visual deprivation effects manifest faster at the cortical level than the geniculate level early in the sensitive period.
    • Cortical dominance shifts can occur even when the geniculate nucleus still shows deprivation effects.
    • Cortical physiology remains sensitive to abnormal visual input beyond the initial sensitive period.

    Conclusions:

    • Abnormal visual stimulation during infancy leads to functional reorganization of visual pathways, not arrested development.
    • The visual system retains plasticity, allowing for reversal of deprivation effects even after maturation.

    Related Experiment Videos